Supporting humoral responses to deal with cancer simply makes sense. Vaccination approaches have long been employed for stopping even the deadliest of diseases (e.g., small pox and tuberculosis). Antibodies can get into virtually every nook and cranny of the body that immune cells can't, and if specific, IgG and complement bind to cancer cells and cause them to rupture and die. Classical techniques use immune challenge followed by a booster of the same challenge. Responses a thousand times greater are possible with such approaches. For aggressive cancers, the tumor itself can be used to challenge with vitalethine provided as immune support or “adjuvant” every 10-14 days.