http://www.vitaletherapeutics.org/vtlcltur.htm
Higher resolutions of the same pictures of mouse spleen cells show additional striking differences between those having vitalethine (on the left) and those depleted of vitalethine by dilution of blood serum (on the right). The few remaining (on the right) that aren't all shriveled up have little bubbles or vacuoles in their cytosol. Vacuoles are often like “stomachs” in the cells, used to digest material that the cell deems worthless or foreign, to recycle it. The few surviving cells may be eating themselves alive, perhaps to make make enough vitalethine to survive. Cells provided vitalethine don't evidence such stress.