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http://www.vitaletherapeutics.org/vtlpo4ps.htm

Vitaletheine (VSH) is probably made right on its monooxygenase receptor through a rearrangement of 4'-phosphopantetheine. It can then be oxidized again via its sulfenic acid (VSOH) to form vitaletheine's disulfide (VSSV), which has actually been observed on its monooxygenase receptor after purification to homogeneity from hog liver. This 4-Phosphopantetheine restored NADPH-dependent iodinating activity in thyroid hormone biosynthesis, indicating that this metabolite is critical to biological pathways regulated by the flavin-containing microsomal monooxygenase for vitalethine.