In the liver, epicatechin (154) produces only a small gamma-tocopherol benefit relative to the effects of sesamin. Alkylresorcinols again have some benefit at 112. Thus, the percent change in gamma-tocopherol is again much higher with sesamin. Diets have long been considered to be a factor in Asian incidences of liver cancer, one probable cause being mycotoxins like aflatoxins from the difficulties encountered in drying and storing grain in moist climates. Pollution has long been a major and growing problem in large cities in Asia, and this shows no sign of abating any time in the near future. Couple this concern with diets that can be rather marginal as far as protein is concerned, and the fact that the oceans' fish are becoming too contaminated with metal toxins to eat..